Case Of Autoimmune Disorders Samples †MyAssignmenthelp.com

Question: Discuss about the Case Of Autoimmune Disorders. Answer: Autoimmune disorders are a very common disorder which is a severe health condition that facilitated the autoimmune system to attack the host body system. It has to be mentioned that immune system generally provides the innate defense system to the body to fight against any foreign substance in the body. In case of autoimmune disorders human body cannot make any difference from foreign cells and on body cells and the autoimmune disorders often have multiple disorders, which is often facilitated by genetic predisposition (CopsteadBanasik, 2013). In the case study that was assessed in the assignment represented of 14 year old girl with a recent history of tender temporomandibular joint sand regular morning stiffness in both of our hips. As a result she has limited range of movement in the hips, especially in case of abduction and adduction and was no longer able to run and play games as a normal child. On diagnosis the patients showed beginning science of fusion of sacroiliac joints and early onset of destruction of the hip joints (CopsteadBanasik, 2013). In this case the patient had a rare form of autoimmune disorder known as the spondyloarthropathy which is hereditary family of closely related disorders including ankylosing spondylitis, reactive arthritis, psoriatic arthritis, along with inflammatory bowel disease. The main causing factor is the human leukocyte antigen HLA-B27 and a common Pathology enthesitis. There are various genetic and environmental factors that act as triggers for this autoimmune disorder. This disease is generated by the tissue damage that is present in the joint of ankylosing spondylitis patients mediated by the Black restricted CD8+ cytotoxic lymphocytes that responds to self antigens expressed in the joint, leading to the regenerative disorder and tissue damage (Arvikar et al., 2017). References: Arvikar, S. L., Crowley, J. T., Sulka, K. B., Steere, A. C. (2017). Autoimmune arthritides, rheumatoid arthritis, psoriatic arthritis, or peripheral spondyloarthritis following Lyme disease.Arthritis Rheumatology,69(1), 194-202. Copstead.,L.C.Banasik.J.L.(2013).Pathophysiology (5th ed.)..Retrieved from https://www.academia.edu/13797058/Pathophysiology_5E_PDF.